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Curcumin binds in silico to anti-cancer drug target enzyme MMP-3 (human stromelysin-1) with affinity comparable to two known inhibitors of the enzyme

In silico interaction of curcumin with the enzyme MMP-3 (human stromelysin-1) was studied by molecular docking using AutoDock 4.2 as the docking software application. AutoDock 4.2 software serves as a valid and acceptable docking application to study the interactions of small compounds with proteins...

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Detalhes bibliográficos
Publicado no:Bioinformation
Main Authors: Jerah, Ahmed, Hobani, Yahya, Kumar, B Vinod, Bidwai, Anil
Formato: Artigo
Idioma:Inglês
Publicado em: Biomedical Informatics 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4574121/
https://ncbi.nlm.nih.gov/pubmed/26420919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.6026/97320630011387
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