NT-020 treatment reduces inflammation and augments Nrf-2 and Wnt signaling in aged rats

BACKGROUND: Aging is associated with a decline in stem cell proliferation that is thought to be a result of dysregulated signaling in the neurogenic niche. This results in a diminished and less efficient pool of progenitors. The Wnt pathway plays a key role in the proliferation and differentiation o...

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Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: Flowers, Antwoine, Lee, Jea-Young, Acosta, Sandra, Hudson, Charles, Small, Brent, Sanberg, Cyndy D., Bickford, Paula C.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4574066/
https://ncbi.nlm.nih.gov/pubmed/26376629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-015-0395-4
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