Targeting Mortalin by Embelin Causes Activation of Tumor Suppressor p53 and Deactivation of Metastatic Signaling in Human Breast Cancer Cells

Embelin, a natural quinone found in the fruits of Embelia ribes, is commonly used in Ayurvedic home medicine for a variety of therapeutic potentials including anti-inflammation, anti-fever, anti-bacteria and anti-cancer. Molecular mechanisms of these activities and cellular targets have not been cla...

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Publicado en:PLoS One
Autores principales: Nigam, Nupur, Grover, Abhinav, Goyal, Sukriti, Katiyar, Shashank P., Bhargava, Priyanshu, Wang, Pi-Chao, Sundar, Durai, Kaul, Sunil C., Wadhwa, Renu
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2015
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4574062/
https://ncbi.nlm.nih.gov/pubmed/26376435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0138192
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