Molecular genotyping of papillary thyroid carcinoma follicular variant according to its histological subtypes (encapsulated vs infiltrative) reveals distinct BRAF and RAS mutation patterns

The follicular variant of papillary thyroid carcinoma usually presents as an encapsulated tumor and less commonly as a partially/non-encapsulated infiltrative neoplasm. The encapsulated form rarely metastasizes to lymph node, whereas infiltrative tumor often harbors nodal metastases. The molecular p...

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Veröffentlicht in:Mod Pathol
Hauptverfasser: Rivera, Michael, Ricarte-Filho, Julio, Knauf, Jeff, Shaha, Ashok, Tuttle, Michael, Fagin, James A, Ghossein, Ronald A
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4573468/
https://ncbi.nlm.nih.gov/pubmed/20526288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/modpathol.2010.112
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