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Elimination of Human Lung Cancer Stem Cells through Targeting of the Stem Cell Factor–c-kit Autocrine Signaling Loop

Cancer stem cells (CSC) are thought to be responsible for tumor initiation and tumor regeneration after chemotherapy. Previously, we showed that chemotherapy of non–small cell lung cancer (NSCLC) cells lines can select for outgrowth of highly tumorigenic and metastatic CSCs. The high malignancy of l...

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Dettagli Bibliografici
Pubblicato in:Cancer Res
Autori principali: Levina, Vera, Marrangoni, Adele, Wang, Tingting, Parikh, Simul, Su, Yunyun, Herberman, Ronald, Lokshin, Anna, Gorelik, Elieser
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4572892/
https://ncbi.nlm.nih.gov/pubmed/20028869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-1102
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