Targeting stem cell niche can protect hematopoietic stem cells from chemotherapy and G-CSF treatment

INTRODUCTION: Hematopoietic stem/progenitor cells (HSPCs) reside in a tightly controlled local microenvironment called bone marrow niche. The specialized microenvironment or niche not only provides a favorable habitat for HSPC maintenance and development but also governs stem cell function. METHOD:...

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Publicado en:Stem Cell Res Ther
Autores principales: Li, Sidan, Zou, Dehui, Li, Changhong, Meng, Hengxing, Sui, Weiwei, Feng, Sizhou, Cheng, Tao, Zhai, Qiongli, Qiu, Lugui
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2015
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Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4572669/
https://ncbi.nlm.nih.gov/pubmed/26373707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-015-0164-4
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