The role of tau in the pathological process and clinical expression of Huntington’s disease

Huntington’s disease is a neurodegenerative disorder caused by an abnormal CAG repeat expansion within exon 1 of the huntingtin gene HTT. While several genetic modifiers, distinct from the Huntington’s disease locus itself, have been identified as being linked to the clinical expression and progress...

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Bibliographic Details
Published in:Brain
Main Authors: Vuono, Romina, Winder-Rhodes, Sophie, de Silva, Rohan, Cisbani, Giulia, Drouin-Ouellet, Janelle, Spillantini, Maria G., Cicchetti, Francesca, Barker, Roger A.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2015
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4572485/
https://ncbi.nlm.nih.gov/pubmed/25953777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awv107
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