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Role of IGF-I in follistatin-induced skeletal muscle hypertrophy

Follistatin, a physiological inhibitor of myostatin, induces a dramatic increase in skeletal muscle mass, requiring the type 1 IGF-I receptor/Akt/mTOR pathway. The aim of the present study was to investigate the role of IGF-I and insulin, two ligands of the IGF-I receptor, in the follistatin hypertr...

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Pubblicato in:Am J Physiol Endocrinol Metab
Autori principali: Barbé, Caroline, Kalista, Stéphanie, Loumaye, Audrey, Ritvos, Olli, Lause, Pascale, Ferracin, Benjamin, Thissen, Jean-Paul
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4572457/
https://ncbi.nlm.nih.gov/pubmed/26219865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00098.2015
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