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The gastrin-releasing peptide analog bombesin preserves exocrine and endocrine pancreas morphology and function during parenteral nutrition

Stimulation of digestive organs by enteric peptides is lost during total parental nutrition (PN). Here we examine the role of the enteric peptide bombesin (BBS) in stimulation of the exocrine and endocrine pancreas during PN. BBS protects against exocrine pancreas atrophy and dysfunction caused by P...

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Veröffentlicht in:Am J Physiol Gastrointest Liver Physiol
Hauptverfasser: Pierre, Joseph F., Neuman, Joshua C., Brill, Allison L., Brar, Harpreet K., Thompson, Mary F., Cadena, Mark T., Connors, Kelsey M., Busch, Rebecca A., Heneghan, Aaron F., Cham, Candace M., Jones, Elaina K., Kibbe, Carly R., Davis, Dawn B., Groblewski, Guy E., Kudsk, Kenneth A., Kimple, Michelle E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4572409/
https://ncbi.nlm.nih.gov/pubmed/26185331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00072.2015
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