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Inhibition of human La protein by RNA interference downregulates hepatitis B virus mRNA in 2.2.15 cells

AIM: To investigate the role of human La protein in HBV mRNA expression. METHODS: Three human La protein (hLa) specific siRNA expression cassettes (SECs) containing U6+1 promoter were prepared via one-step overlapping extension PCR. After transfection with SECs into HepG2 cells, inhibition effects o...

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Detalhes bibliográficos
Publicado no:World J Gastroenterol
Main Authors: Ni, Qin, Chen, Zhi, Yao, Hang-Ping, Yang, Zheng-Gang, Liu, Ke-Zhou, Wu, Ling-Ling
Formato: Artigo
Idioma:Inglês
Publicado em: Baishideng Publishing Group Inc 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4572331/
https://ncbi.nlm.nih.gov/pubmed/15237432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v10.i14.2050
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