The SIRT1 promoter polymorphic site rs12778366 increases IL-6 related human mortality in the prospective study “Treviso Longeva (TRELONG)”

Studies on sirtuins (SIRT), a family of proteins with deacetylase activity, have provided convergent evidence of the key role of these enzymes in aging-linked physiological functions. The link between SIRT1 and longevity has emerged in model organism but few data are available in humans, in particul...

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Bibliografische gegevens
Gepubliceerd in:Int J Mol Epidemiol Genet
Hoofdauteurs: Albani, Diego, Mazzuco, Stefano, Chierchia, Armando, Fusco, Federica, Boeri, Lucia, Martines, Rosalba, Giorgi, Enrico Di, Frigato, Andrea, Durante, Elisabetta, Caberlotto, Livio, Zanardo, Andrea, Siculi, Marinella, Gallucci, Maurizio, Forloni, Gianluigi
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: e-Century Publishing Corporation 2015
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Original Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4572089/
https://ncbi.nlm.nih.gov/pubmed/26417401
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