Tetracycline-grafted PLGA nanoparticles as bone-targeting drug delivery system

PURPOSE: Nanoparticles (NPs) that target bone tissue were developed using poly(lactic-co-glycolic acid) (PLGA) copolymers and tetracycline (TC)-based bone-targeting moieties. These NPs are expected to enable the transport of drugs, such as simvastatin (SIM), for the treatment of osteoporosis. METHOD...

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Bibliografiske detaljer
Udgivet i:Int J Nanomedicine
Main Authors: Wang, Hua, Liu, Jun, Tao, Shan, Chai, Guihong, Wang, Jianwei, Hu, Fu-Qiang, Yuan, Hong
Format: Artigo
Sprog:Inglês
Udgivet: Dove Medical Press 2015
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4571930/
https://ncbi.nlm.nih.gov/pubmed/26388691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S88798
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