Retinylamine Benefits Early Diabetic Retinopathy in Mice

Recent evidence suggests an important role for outer retinal cells in the pathogenesis of diabetic retinopathy (DR). Here we investigated the effect of the visual cycle inhibitor retinylamine (Ret-NH(2)) on the development of early DR lesions. Wild-type (WT) C57BL/6J mice (male, 2 months old when di...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Liu, Haitao, Tang, Jie, Du, Yunpeng, Lee, Chieh Allen, Golczak, Marcin, Muthusamy, Arivalagan, Antonetti, David A., Veenstra, Alexander A., Amengual, Jaume, von Lintig, Johannes, Palczewski, Krzysztof, Kern, Timothy S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Molecular Bases of Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4571881/
https://ncbi.nlm.nih.gov/pubmed/26139608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.655555
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