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Biogenesis of the yeast lysosome (vacuole): biosynthesis and maturation of proteinase yscB.

The biosynthesis and processing of the vacuolar (lysosomal) proteinase yscB was followed in vivo and in vitro. In vitro transcription--translation of the cloned proteinase yscB gene results in a high mol. wt precursor protein (HMr-precursor) of Mr = 73,000. In vivo a precursor of identical mol. wt i...

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Udgivet i:EMBO J
Principais autores: Mechler, B, Hirsch, H H, Müller, H, Wolf, D H
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 1988
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC457157/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3049073/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1988.tb02999.x
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