Regulation of cell proliferation by ERK and signal-dependent nuclear translocation of ERK is dependent on Tm5NM1-containing actin filaments

ERK-regulated cell proliferation requires multiple phosphorylation events catalyzed first by MEK and then by casein kinase 2 (CK2), followed by interaction with importin7 and subsequent nuclear translocation of pERK. We report that genetic manipulation of a core component of the actin filaments of c...

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Publicado no:Mol Biol Cell
Main Authors: Schevzov, Galina, Kee, Anthony J., Wang, Bin, Sequeira, Vanessa B., Hook, Jeff, Coombes, Jason D., Lucas, Christine A., Stehn, Justine R., Musgrove, Elizabeth A., Cretu, Alexandra, Assoian, Richard, Fath, Thomas, Hanoch, Tamar, Seger, Rony, Pleines, Irina, Kile, Benjamin T., Hardeman, Edna C., Gunning, Peter W.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2015
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4571302/
https://ncbi.nlm.nih.gov/pubmed/25971798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E14-10-1453
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