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Antisense RNA inhibits splicing of pre-mRNA in vitro.

Antisense RNAs complementary to human beta-globin pre-mRNA or to a chimeric globin/adenovirus E2a pre-mRNA specifically and efficiently inhibit pre-mRNA splicing in vitro. The level of inhibition depends on the length, position and concentration of the antisense RNA relative to the pre-mRNA substrat...

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Bibliografiske detaljer
Udgivet i:EMBO J
Hovedforfatter: Munroe, S H
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 1988
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC457123/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2461296/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1988.tb03100.x
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