Molecular cloning and characterization of the human dbl proto-oncogene: evidence that its overexpression is sufficient to transform NIH/3T3 cells.

We isolated cDNA clones representing the human dbl proto-oncogene transcript. Nucleotide sequence analysis revealed an open reading frame encoding a predicted protein of 925 amino acids. Using peptide antisera directed against specific proto-dbl peptides, a 115-kd protein was detected in COS cells t...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Ron, D, Tronick, S R, Aaronson, S A, Eva, A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1988
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC457116/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3056717/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1988.tb03093.x
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