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Role of XmnI(G) Polymorphism in Hydroxyurea Treatment and Fetal Hemoglobin Level at Isfahanian Intermediate β-Thalassemia Patients
BACKGROUND: β-thalassemia is the most common monogenic disorder in human. The (CT) polymorphism at -158 upstream region of the γ(G)-globin gene and pharmacological factors such as hydroxyurea have been reported to influence γ-globin gene expression and the severity of clinical symptoms of β-thalasse...
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| Published in: | Iran Biomed J |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Pasteur Institute of Iran
2015
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4571014/ https://ncbi.nlm.nih.gov/pubmed/26024726 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7508/ibj.2015.03.008 |
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