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Effect of Oxidized Low Density Lipoprotein on the Expression of Runx2 and SPARC Genes in Vascular Smooth Muscle Cells

BACKGROUND: Vascular calcification is an important stage in atherosclerosis. During this stage, vascular smooth muscle cells (VSMC) synthesize many osteogenic factors such as osteonectin (encoded by SPARC). Oxidative stress plays a critical role in atherosclerosis progression, and its accumulation i...

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Detalhes bibliográficos
Publicado no:Iran Biomed J
Main Authors: Farrokhi, Effat, Ghatreh Samani, Keihan, Hashemzadeh, Morteza, Tabatabaiefar, Mohammad Amin
Formato: Artigo
Idioma:Inglês
Publicado em: Pasteur Institute of Iran 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4571011/
https://ncbi.nlm.nih.gov/pubmed/26025968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7508/ibj.2015.03.005
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