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Association of insulin resistance with cerebral glucose uptake in late middle-aged adults at risk for Alzheimer’s disease

IMPORTANCE: Converging evidence suggests that Alzheimer’s disease (AD) involves insulin signaling impairment. AD patients and people at risk for AD show reduced glucose metabolism, as indexed by F18-fluorodeoxyglucose positron emission tomography ([F18]FDG-PET). OBJECTIVE: To determine if insulin re...

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Bibliographische Detailangaben
Veröffentlicht in:JAMA Neurol
Hauptverfasser: Willette, Auriel A., Bendlin, Barbara B., Starks, Erika J., Birdsill, Alex C., Johnson, Sterling C., Christian, Bradley T., Okonkwo, Ozioma C., La Rue, Asenath, Hermann, Bruce P., Koscik, Rebecca L., Jonaitis, Erin M., Sager, Mark A., Asthana, Sanjay
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4570876/
https://ncbi.nlm.nih.gov/pubmed/26214150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaneurol.2015.0613
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