Novel Nut and Bolt Task Quantifies Motor Deficits in Premanifest and Manifest Huntington’s Disease

Background: We investigated the use of a simple novel nut and bolt task in premanifest and manifest Huntington’s disease (HD) patients to detect and quantify motor impairments at all stages of the disease. Methods: Premanifest HD (n=24), manifest HD (n=27) and control (n=32) participants were asked...

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Publicat a:PLoS Curr
Autors principals: Collins, Lucy M., Begeti, Faye, Panin, Francesca, Lazar, Alpar S., Cruickshank, Travis, Ziman, Mel, Mason, Sarah L., Barker, Roger A.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4570842/
https://ncbi.nlm.nih.gov/pubmed/26421223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/currents.hd.ded251617ae62a1364506b0521bd3761
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