CDKN3 mRNA as a Biomarker for Survival and Therapeutic Target in Cervical Cancer

The cyclin-dependent kinase inhibitor 3 (CDKN3) gene, involved in mitosis, is upregulated in cervical cancer (CC). We investigated CDKN3 mRNA as a survival biomarker and potential therapeutic target for CC. CDKN3 mRNA was measured in 134 CC and 25 controls by quantitative PCR. A 5-year survival stud...

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Veröffentlicht in:PLoS One
Hauptverfasser: Barrón, Eira Valeria, Roman-Bassaure, Edgar, Sánchez-Sandoval, Ana Laura, Espinosa, Ana María, Guardado-Estrada, Mariano, Medina, Ingrid, Juárez, Eligia, Alfaro, Ana, Bermúdez, Miriam, Zamora, Rubén, García-Ruiz, Carlos, Gomora, Juan Carlos, Kofman, Susana, Pérez-Armendariz, E. Martha, Berumen, Jaime
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4570808/
https://ncbi.nlm.nih.gov/pubmed/26372210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0137397
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