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Structural and mutational analysis of E2 trans-activating proteins of papillomaviruses reveals three distinct functional domains.

The E2 proteins of papillomaviruses are able to transactivate the viral enhancers by interacting with the sequence ACCGN4CGGT found in all papillomavirus long control regions. Analysis of the alignment of the amino acid sequences of 10 E2 proteins reveals three distinct regions: two partially conser...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Giri, I, Yaniv, M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1988
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC457074/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2846285/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1988.tb03138.x
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