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Applicability of HIN-1, MGMT and RASSF1A promoter methylation as biomarkers for detecting field cancerization in breast cancer

INTRODUCTION: It has been shown in some articles that genetic and epigenetic abnormalities cannot only be found in tumor tissues but also in adjacent regions that appear histologically normal. This phenomenon is metaphorically called field cancerization or field defect. Field cancerization is regard...

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Detalhes bibliográficos
Publicado no:Breast Cancer Res
Main Authors: Spitzwieser, Melanie, Holzweber, Elisabeth, Pfeiler, Georg, Hacker, Stefan, Cichna-Markl, Margit
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4570691/
https://ncbi.nlm.nih.gov/pubmed/26370119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13058-015-0637-5
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