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Multiple mechanisms regulate c-myc gene expression during normal T cell activation.

Quiescent normal human T cells express low levels of steady-state c-myc mRNA as a result of low constitutive promoter utilization, a block to transcriptional elongation within the gene, and rapid degradation of c-myc mRNA in the cytoplasm. Following the activation of the T cell receptor (TCR)/CD3 co...

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Bibliografske podrobnosti
Main Authors: Lindsten, T, June, C H, Thompson, C B
Format: Artigo
Jezik:Inglês
Izdano: 1988
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC457069/
https://ncbi.nlm.nih.gov/pubmed/3053165
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