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Oral supplementation of diabetic mice with propolis restores the proliferation capacity and chemotaxis of B and T lymphocytes towards CCL21 and CXCL12 by modulating the lipid profile, the pro-inflammatory cytokine levels and oxidative stress

BACKGROUND: Type 1 diabetes mellitus (T1D) is a chronic autoimmune disease caused by the selective destruction of pancreatic β cells, followed by hyperglycemia, oxidative stress and the subsequent extensive impairment of immune cell functions, a phenomenon responsible for the development of chronic...

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Detalhes bibliográficos
Publicado no:BMC Immunol
Main Authors: Al Ghamdi, Ahmad A., Badr, Gamal, Hozzein, Wael N., Allam, Ahmed, Al-Waili, Noori S., Al-Wadaan, Mohammed A., Garraud, Olivier
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4570673/
https://ncbi.nlm.nih.gov/pubmed/26370805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12865-015-0117-9
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