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Structural mapping of the ClpB ATPases of Plasmodium falciparum: Targeting protein folding and secretion for antimalarial drug design

Caseinolytic chaperones and proteases (Clp) belong to the AAA+ protein superfamily and are part of the protein quality control machinery in cells. The eukaryotic parasite Plasmodium falciparum, the causative agent of malaria, has evolved an elaborate network of Clp proteins including two distinct Cl...

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Detalhes bibliográficos
Publicado no:Protein Sci
Main Authors: AhYoung, Andrew P, Koehl, Antoine, Cascio, Duilio, Egea, Pascal F
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4570544/
https://ncbi.nlm.nih.gov/pubmed/26130467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2739
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