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Modeling the energetic cost of cancer as a result of altered energy metabolism: implications for cachexia

BACKGROUND: Cachexia affects most patients with incurable cancer. We hypothesize that in metastatic cancer the mass of the tumor as well as its level of anaerobic energy metabolism play a critical role in describing its energetic cost, which results in elevated resting energy expenditure and glucose...

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Udgivet i:Theor Biol Med Model
Main Authors: Friesen, Douglas E., Baracos, Vickie E., Tuszynski, Jack A.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4570294/
https://ncbi.nlm.nih.gov/pubmed/26370269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12976-015-0015-0
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