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Detecting associations of rare variants with common diseases: collapsing or haplotyping?

In recent years, a myriad of new statistical methods have been proposed for detecting associations of rare single-nucleotide variants (SNVs) with common diseases. These methods can be generally classified as ‘collapsing’ or ‘haplotyping’ based. The former is the predominant class, composed of most o...

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Enregistré dans:
Détails bibliographiques
Publié dans:Brief Bioinform
Auteurs principaux: Wang, Meng, Lin, Shili
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4570202/
https://ncbi.nlm.nih.gov/pubmed/25596401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bib/bbu050
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