A metabolomics-based strategy for identification of gene targets for phenotype improvement and its application to 1-butanol tolerance in Saccharomyces cerevisiae

BACKGROUND: Traditional approaches to phenotype improvement include rational selection of genes for modification, and probability-driven processes such as laboratory evolution or random mutagenesis. A promising middle-ground approach is semi-rational engineering, where genetic modification targets a...

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Detalhes bibliográficos
Publicado no:Biotechnol Biofuels
Main Authors: Teoh, Shao Thing, Putri, Sastia, Mukai, Yukio, Bamba, Takeshi, Fukusaki, Eiichiro
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4570087/
https://ncbi.nlm.nih.gov/pubmed/26379776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13068-015-0330-z
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