Observation of Distressed Conspecific as a Model of Emotional Trauma Generates Silent Synapses in the Prefrontal-Amygdala Pathway and Enhances Fear Learning, but Ketamine Abolishes those Effects

Witnessing pain and distress in others can cause psychological trauma and increase odds of developing PTSD in the future, on exposure to another stressful event. However, the underlying synaptic process remains unknown. Here we report that mice exposed to a conspecific receiving electrical footshock...

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Detaylı Bibliyografya
Yayımlandı:Neuropsychopharmacology
Asıl Yazarlar: Ito, Wataru, Erisir, Alev, Morozov, Alexei
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2015
Konular:
Original Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4569943/
https://ncbi.nlm.nih.gov/pubmed/25865929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2015.100
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