Genetically-encoded tools for cAMP probing and modulation in living systems

Intracellular 3′-5′-cyclic adenosine monophosphate (cAMP) is one of the principal second messengers downstream of a manifold of signal transduction pathways, including the ones triggered by G protein-coupled receptors. Not surprisingly, biochemical assays for cAMP have been instrumental for basic re...

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Bibliographic Details
Published in:Front Pharmacol
Main Authors: Paramonov, Valeriy M., Mamaeva, Veronika, Sahlgren, Cecilia, Rivero-Müller, Adolfo
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2015
Subjects:
Pharmacology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4569861/
https://ncbi.nlm.nih.gov/pubmed/26441653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2015.00196
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