Activation and cytokine profile of monocyte derived dendritic cells in leprosy: in vitro stimulation by sonicated Mycobacterium leprae induces decreased level of IL-12p70 in lepromatous leprosy

Dendritic cells (DCs) play a pivotal role in the connection of innate and adaptive immunity of hosts to mycobacterial infection. Studies on the interaction of monocyte-derived DCs (MO-DCs) using Mycobacterium leprae in leprosy patients are rare. The present study demonstrated that the differentiatio...

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Dades bibliogràfiques
Publicat a:Mem Inst Oswaldo Cruz
Autors principals: Braga, André Flores, Moretto, Daniela Ferraz, Gigliotti, Patrícia, Peruchi, Mariela, Vilani-Moreno, Fátima Regina, Campanelli, Ana Paula, Latini, Ana Carla Pereira, Iyer, Anand, Das, Pranab Kumar, de Souza, Vânia Nieto Brito
Format: Artigo
Idioma:Inglês
Publicat: Instituto Oswaldo Cruz, Ministério da Saúde 2015
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4569830/
https://ncbi.nlm.nih.gov/pubmed/26222022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1590/0074-02760140230
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