Cholesteryl Pullulan Encapsulated TNF-α Nanoparticles Are an Effective Mucosal Vaccine Adjuvant against Influenza Virus

We encapsulated tumor necrosis factor-α (TNF-α), a major proinflammatory cytokine, into cholesteryl pullulan (CHP) to prepare TNF/CHP nanoparticles. In this report, we describe the immune-enhancing capability of the nanoparticles to act as a vaccine adjuvant. TNF/CHP nanoparticles showed excellent s...

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Detalhes bibliográficos
Publicado no:Biomed Res Int
Main Authors: Nagatomo, Daiki, Taniai, Madoka, Ariyasu, Harumi, Taniguchi, Mutsuko, Aga, Miho, Ariyasu, Toshio, Ohta, Tsunetaka, Fukuda, Shigeharu
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4569761/
https://ncbi.nlm.nih.gov/pubmed/26421290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/471468
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