JAK2/STAT3 Inhibitors Attenuate the Effect of Cardiotrophin-Like Cytokine Factor-1 and Human Focal Segmental Glomerulosclerosis Serum on Glomerular Filtration Barrier

Recurrence of idiopathic focal segmental glomerulosclerosis (FSGS) after renal transplantation is believed to be caused by a circulating factor(s). We detected cardiotrophin-like cytokine 1 (CLCF1), a member of the IL-6 family, in the plasma from patients with recurrent FSGS. We hypothesized that CL...

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發表在:Transl Res
Main Authors: Sharma, Mukut, Zhou, Jianping, Gauchat, Jean-François, Sharma, Ram, McCarthy, Ellen T., Srivastava, Tarak, Savin, Virginia J.
格式: Artigo
語言:Inglês
出版: 2015
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4569535/
https://ncbi.nlm.nih.gov/pubmed/25843671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.trsl.2015.03.002
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