Pro-Oxidant Activity of Amine-Pyridine-Based Iron Complexes Efficiently Kills Cancer and Cancer Stem-Like Cells

Differential redox homeostasis in normal and malignant cells suggests that pro-oxidant-induced upregulation of cellular reactive oxygen species (ROS) should selectively target cancer cells without compromising the viability of untransformed cells. Consequently, a pro-oxidant deviation well-tolerated...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: González-Bártulos, Marta, Aceves-Luquero, Clara, Qualai, Jamal, Cussó, Olaf, Martínez, Mª Angeles, Fernández de Mattos, Silvia, Menéndez, Javier A., Villalonga, Priam, Costas, Miquel, Ribas, Xavi, Massaguer, Anna
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4569415/
https://ncbi.nlm.nih.gov/pubmed/26368127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0137800
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