Nasal Lipopolysaccharide Challenge and Cytokine Measurement Reflects Innate Mucosal Immune Responsiveness

BACKGROUND: Practical methods of monitoring innate immune mucosal responsiveness are lacking. Lipopolysaccharide (LPS) is a component of the cell wall of Gram negative bacteria and a potent activator of Toll-like receptor (TLR)-4. To measure LPS responsiveness of the nasal mucosa, we administered LP...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Dhariwal, Jaideep, Kitson, Jeremy, Jones, Reema E., Nicholson, Grant, Tunstall, Tanushree, Walton, Ross P., Francombe, Grace, Gilbert, Jane, Tan, Andrew J., Murdoch, Robert, Kon, Onn Min, Openshaw, Peter J., Hansel, Trevor T.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4569396/
https://ncbi.nlm.nih.gov/pubmed/26367003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0135363
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