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Evolution of the Antisense Overlap between Genes for Thyroid Hormone Receptor and Rev-erbα and Characterization of an Exonic G-Rich Element That Regulates Splicing of TRα2 mRNA

The α-thyroid hormone receptor gene (TRα) codes for two functionally distinct proteins: TRα1, the α-thyroid hormone receptor; and TRα2, a non-hormone-binding variant. The final exon of TRα2 mRNA overlaps the 3’ end of Rev-erbα mRNA, which encodes another nuclear receptor on the opposite strand of DN...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Munroe, Stephen H., Morales, Christopher H., Duyck, Tessa H., Waters, Paul D.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4569393/
https://ncbi.nlm.nih.gov/pubmed/26368571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0137893
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