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Which and How Many Patients Should Be Included in Randomised Controlled Trials to Demonstrate the Efficacy of Biologics in Primary Sjögren’s Syndrome?

OBJECTIVE: The goal of this study was to determine how the choice of the primary endpoint influenced sample size estimates in randomised controlled trials (RCTs) of treatments for primary Sjögren’s syndrome (pSS). METHODS: We reviewed all studies evaluating biotechnological therapies in pSS to ident...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:PLoS One
मुख्य लेखकों: Devauchelle-Pensec, Valérie, Gottenberg, Jacques-Eric, Jousse-Joulin, Sandrine, Berthelot, Jean-Marie, Perdriger, Aleth, Hachulla, Eric, Hatron, Pierre Yves, Puechal, Xavier, Le Guern, Véronique, Sibilia, Jean, Chiche, Laurent, Goeb, Vincent, Vittecoq, Olivier, Larroche, Claire, Fauchais, Anne Laure, Hayem, Gilles, Morel, Jacques, Zarnitsky, Charles, Dubost, Jean Jacques, Dieudé, Philippe, Pers, Jacques Olivier, Cornec, Divi, Seror, Raphaele, Mariette, Xavier, Nowak, Emmanuel, Saraux, Alain
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Public Library of Science 2015
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4569343/
https://ncbi.nlm.nih.gov/pubmed/26368934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0133907
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