ER Stress Mediates TiAl(6)V(4) Particle-Induced Peri-Implant Osteolysis by Promoting RANKL Expression in Fibroblasts

Wear particle-induced osteolysis is a major cause of aseptic loosening, which is one of the most common reasons for total hip arthroplasty (THA) failure. Previous studies have shown that the synovial fibroblasts present in the periprosthetic membrane are important targets of wear debris during osteo...

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Veröffentlicht in:PLoS One
Hauptverfasser: Wang, Zhenheng, Liu, Naicheng, Shi, Tongguo, Zhou, Gang, Wang, Zhenzhen, Gan, Jingjing, Guo, Ting, Qian, Hongbo, Bao, Nirong, Zhao, Jianning
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4569331/
https://ncbi.nlm.nih.gov/pubmed/26366858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0137774
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