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Src and cortactin promote lamellipodia protrusion and filopodia formation and stability in growth cones

Src tyrosine kinases have been implicated in axonal growth and guidance; however, the underlying cellular mechanisms are not well understood. Specifically, it is unclear which aspects of actin organization and dynamics are regulated by Src in neuronal growth cones. Here, we investigated the function...

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Dettagli Bibliografici
Pubblicato in:Mol Biol Cell
Autori principali: He, Yingpei, Ren, Yuan, Wu, Bingbing, Decourt, Boris, Lee, Aih Cheun, Taylor, Aaron, Suter, Daniel M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Cell Biology 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4569314/
https://ncbi.nlm.nih.gov/pubmed/26224308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E15-03-0142
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