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Reference Materials for Calibration of Analytical Biases in Quantification of DNA Methylation

Most contemporary methods for the quantification of DNA methylation employ bisulfite conversion and PCR amplification. However, many reports have indicated that bisulfite-mediated PCR methodologies can result in inaccurate measurements of DNA methylation owing to amplification biases. To calibrate a...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Yu, Hannah, Hahn, Yoonsoo, Yang, Inchul
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4569303/
https://ncbi.nlm.nih.gov/pubmed/26368560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0137006
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