The NLRP3 Inflammasome and IL-1β Accelerate Immunologically Mediated Pathology in Experimental Viral Fulminant Hepatitis

Viral fulminant hepatitis (FH) is a severe disease with high mortality resulting from excessive inflammation in the infected liver. Clinical interventions have been inefficient due to the lack of knowledge for inflammatory pathogenesis in the virus-infected liver. We show that wild-type mice infecte...

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Bibliographic Details
Published in:PLoS Pathog
Main Authors: Guo, Sheng, Yang, Chengying, Diao, Bo, Huang, Xiaoyong, Jin, Meihua, Chen, Lili, Yan, Weiming, Ning, Qin, Zheng, Lixin, Wu, Yuzhang, Chen, Yongwen
Format: Artigo
Language:Inglês
Published: Public Library of Science 2015
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4569300/
https://ncbi.nlm.nih.gov/pubmed/26367131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005155
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