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Chronic Lead Exposure and Mixed Factors of Gender×Age×Brain Regions Interactions on Dendrite Growth, Spine Maturity and NDR Kinase
NDR1/2 kinase is essential in dendrite morphology and spine formation, which is regulated by cellular Ca(2+). Lead (Pb) is a potent blocker of L-type calcium channel and our recent work showed Pb exposure impairs dendritic spine outgrowth in hippocampal neurons in rats. But the sensitivity of Pb-ind...
Shranjeno v:
| izdano v: | PLoS One |
|---|---|
| Main Authors: | , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Public Library of Science
2015
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4569283/ https://ncbi.nlm.nih.gov/pubmed/26368815 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0138112 |
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