Chronic Lead Exposure and Mixed Factors of Gender×Age×Brain Regions Interactions on Dendrite Growth, Spine Maturity and NDR Kinase

NDR1/2 kinase is essential in dendrite morphology and spine formation, which is regulated by cellular Ca(2+). Lead (Pb) is a potent blocker of L-type calcium channel and our recent work showed Pb exposure impairs dendritic spine outgrowth in hippocampal neurons in rats. But the sensitivity of Pb-ind...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Du, Yang, Ge, Meng-Meng, Xue, Weizhen, Yang, Qian-Qian, Wang, Shuang, Xu, Yi, Wang, Hui-Li
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4569283/
https://ncbi.nlm.nih.gov/pubmed/26368815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0138112
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