Emergence of Amoxicillin-Resistant Variants of Spain(9V)-ST156 Pneumococci Expressing Serotype 11A Correlates with Their Ability to Evade the Host Immune Response

Capsular switching allows pre-existing clones of Streptococcus pneumoniae expressing vaccine serotypes to escape the vaccine-induced immunity by acquisition of capsular genes from pneumococci of a non-vaccine serotype. Here, we have analysed the clonal composition of 492 clinical isolates of serotyp...

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Veröffentlicht in:PLoS One
Hauptverfasser: Aguinagalde, Leire, Corsini, Bruno, Domenech, Arnau, Domenech, Mirian, Cámara, Jordi, Ardanuy, Carmen, García, Ernesto, Liñares, Josefina, Fenoll, Asunción, Yuste, Jose
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4569277/
https://ncbi.nlm.nih.gov/pubmed/26368279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0137565
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