Cardiac LXRα protects against pathological cardiac hypertrophy and dysfunction by enhancing glucose uptake and utilization

Pathological cardiac hypertrophy is characterized by a shift in metabolic substrate utilization from fatty acids to glucose, but the molecular events underlying the metabolic remodeling remain poorly understood. Here, we investigated the role of liver X receptors (LXRs), which are key regulators of...

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Sparad:
Bibliografiska uppgifter
I publikationen:EMBO Mol Med
Huvudupphovsmän: Cannon, Megan V, Silljé, Herman HW, Sijbesma, Jürgen WA, Vreeswijk-Baudoin, Inge, Ciapaite, Jolita, van der Sluis, Bart, van Deursen, Jan, Silva, Gustavo JJ, de Windt, Leon J, Gustafsson, Jan-Åke, van der Harst, Pim, van Gilst, Wiek H, de Boer, Rudolf A
Materialtyp: Artigo
Språk:Inglês
Publicerad: John Wiley & Sons, Ltd 2015
Ämnen:
Research Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4568954/
https://ncbi.nlm.nih.gov/pubmed/26160456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201404669
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