TEX11 is mutated in infertile men with azoospermia and regulates genome-wide recombination rates in mouse

Genome-wide recombination is essential for genome stability, evolution, and speciation. Mouse Tex11, an X-linked meiosis-specific gene, promotes meiotic recombination and chromosomal synapsis. Here, we report that TEX11 is mutated in infertile men with non-obstructive azoospermia and that an analogo...

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Publicat a:EMBO Mol Med
Autors principals: Yang, Fang, Silber, Sherman, Leu, N Adrian, Oates, Robert D, Marszalek, Janet D, Skaletsky, Helen, Brown, Laura G, Rozen, Steve, Page, David C, Wang, P Jeremy
Format: Artigo
Idioma:Inglês
Publicat: John Wiley & Sons, Ltd 2015
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4568952/
https://ncbi.nlm.nih.gov/pubmed/26136358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201404967
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