Apelin promotes diabetic nephropathy by inducing podocyte dysfunction via inhibiting proteasome activities

Podocyte injuries are associated with progression of diabetic nephropathy (DN). Apelin, an adipocyte-derived peptide, has been reported to be a promoting factor for DN. In this study, we aim to determine whether apelin promotes progression of DN by inducing podocyte dysfunction. kk-Ay mice were used...

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Publicat a:J Cell Mol Med
Autors principals: Guo, Caixia, Liu, Yu, Zhao, Wenjie, Wei, Shengnan, Zhang, Xiaoli, Wang, Wenying, Zeng, Xiangjun
Format: Artigo
Idioma:Inglês
Publicat: John Wiley & Sons, Ltd 2015
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Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4568931/
https://ncbi.nlm.nih.gov/pubmed/26103809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.12619
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