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Late emergence of A594V and L595W mutations related to ganciclovir resistance in a patient with HCMV retinitis and long-term HIV progression

The emergence of ganciclovir (GCV) resistance during the treatment of human cytomegalovirus (HCMV) infection is a serious clinical challenge, and is associated with high morbidity and mortality. In this case report, we describe the emergence of two consecutive mutations (A594V and L595W) related to...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Braz J Med Biol Res
Prif Awduron: Slavov, S.N., Vilar, F.C., Wagatsuma, V.M.D., Santana, R.C., Machado, A.A., da Fonseca, B.A.L., Kashima, S., Covas, D.T.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Associação Brasileira de Divulgação Científica 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4568804/
https://ncbi.nlm.nih.gov/pubmed/26270327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1590/1414-431X20154507
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